![]() ![]() The Parkinson’s Disease Foundation reports that approximately 1 million Americans currently have the disease. PD is one of the most common neurodegenerative disorders. ![]() Evidence for this preclinical phase has driven the enthusiasm for research that focuses on protective or preventive therapies. Research suggests that the pathophysiological changes associated with PD may start before the onset of motor features and may include a number of nonmotor presentations, such as sleep disorders, depression, and cognitive changes. PD is the most common cause of parkinsonism, although a number of secondary causes also exist, including diseases that mimic PD and drug-induced causes. The term parkinsonism is a symptom complex used to describe the motor features of PD, which include resting tremor, bradykinesia, and muscular rigidity. The motor symptoms of PD are attributed to the loss of striatal dopaminergic neurons, although the presence of nonmotor symptoms supports neuronal loss in nondopaminergic areas as well. ![]() The disease has a significant clinical impact on patients, families, and caregivers through its progressive degenerative effects on mobility and muscle control. James Parkinson in 1817 as a “shaking palsy.” It is a chronic, progressive neurodegenerative disease characterized by both motor and nonmotor features. Parkinson’s disease (PD) was first described by Dr. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |